At PDR a main focus has always been facilitating and encouraging a very deterministic and largely automated “assembly line” from molecule development to purified molecules by: (a) rapidly screening separation methods, (b) selecting the best method for purification pragmatically, and then (c) purifying from milligrams to tons efficiently and with as much automation as possible.
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DALP
Optical Activity Detector
Digital Advanced Laser Polarimeter accurately measures optical activity without regard for absorbance or chromophores.
All – Digital electronics and processing algorithms remove the effects of laser power variations to reduce noise and improve performance.
AutoMDS Systems
Automated Method Development
PDR started developing AutoMDS and AutoPREP Software in 1998. PDR still continues aggressive development and improvement of AutoMDS and AutoPREP software. AutoMDS can run continuously without attention; assuming adequate solvent, waste, and sample solution.
AutoPREP Systems
Automated Preparative Purification
PDR started developing AutoMDS and AutoPREP Software in 1998. PDR still continues aggressive development and improvement of AutoMDS and AutoPREP software. AutoPREP can run continuously without attention; assuming adequate solvent, waste, and sample solution.
Deconvolution
Spectral and Chiral
PDR’s Spectral Deconvolution is real-time and can plot the concentration of individual molecules, even if spectra are very similar. PDR’s Spectral Deconvolution can be applied at any scale from analytical using Agilent DAD to large scale using an inline fibre-optic spectrometer.
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DALP (Digital Advanced Laser Polarimeter) Optical Activity Detector
DALP is a new digital implementation of our traditional ALP (Advanced Laser Polarimeter) that has been in production for more than 20 years. DALP uses digital signal processing (DSP) with our proprietary algorithms to successfully ignore changes in laser power and absorbance to consistently delivery improved sensitivity, drift, and accuracy. PDR’s companion DALP App sets time constant and supports on-site optimization, calibration, and software upgrades. Existing ALPs can be upgraded to DALP with all-new electronics and improved capabilities for about $10K.
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AutoMDS Systems (Automated Method Development)
PDR started developing AutoMDS and AutoPREP Software in 1998, and still continues aggressive development and improvement of AutoMDS and AutoPREP software. AutoMDS can run continuously without attention; assuming adequate solvent, waste, and sample solution.
AutoMDS is the ideal program for automated method development. Method and sequence editors use a simple spreadsheet format making it easy to build, edit, and use large method screening sequences. An AutoMDS installation includes methods and sequences specifically built for your applications.
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AutoPREP Systems (Automated Preparative Purification)
PDR started developing AutoMDS and AutoPREP Software in 1998, and still continues aggressive development and improvement of AutoMDS and AutoPREP software. AutoPREP can run continuously without attention; assuming adequate solvent, waste, and sample solution.
AutoPREP is very easy to use and can reliably make 1000s of unattended injections for big jobs. The Recalculate feature instantly shows result of peak detection and collection changes on a test run chromatogram, eliminating the need for more test runs and making setup quick and easy to optimize. If method settings are changed while method is running, AutoPREP adapts appropriately and records changes.
Spectral and Chiral
Real-Time Spectral Deconvolution
PDR’s Spectral Deconvolution is real-time and can plot the concentration of individual molecules, even if spectra are very similar.
PDR’s Spectral Deconvolution can be applied at any scale from analytical using Agilent DAD to large scale using an inline fibre-optic spectrometer.
Applications from analytical peak purity to process monitoring.